Druggability evaluation of a protamine‐like peptide
نویسندگان
چکیده
منابع مشابه
A practical view of 'druggability'.
The introduction of Lipinski's 'Rule of Five' has initiated a profound shift in the thinking paradigm of medicinal chemists. Understanding the difference between biologically active small molecules and drugs became a priority in the drug discovery process, and the importance of addressing pharmacokinetic properties early during lead optimization is a clear result. These concepts of 'drug-likene...
متن کاملa criical evaluation of prospect 1: iranian junior high school english book
این پایان نامه کتاب زبان انگلیسی پایه هفتم(پراسپکت 1) را بر اساس چک لیست کانینگ ورث (1995) مورد ارزیابی قراردهده و نقاط قوت و ضعب کتاب مذکور را بررسی می نماید. در گام دوم نیز از طریق مصاحبه با تعدادی از دبیران زبان انگلیسی که کتاب مورد نظر را تدریس می کنند، نظر دبیران را در مورد پراسپک 1 جویا می شود.
Synthesis of a peptide derivative of microcin J25 and evaluation of antibacterial and biological activities
Microcin J25 (MccJ25) is a small ribosomally synthesized antimicrobial peptide that is produced by Enterobacteriacea family especially E.coli. The present study focuses on preparation and evaluation of in vitro antimicrobial and biological properties of a new peptide derived from MccJ25. We prepared a MccJ25-derived peptide containing 14 amino acids and a single intra-molecular disulfide bond a...
متن کاملSynthesis of a peptide derivative of microcin J25 and evaluation of antibacterial and biological activities
Microcin J25 (MccJ25) is a small ribosomally synthesized antimicrobial peptide that is produced by Enterobacteriacea family especially E.coli. The present study focuses on preparation and evaluation of in vitro antimicrobial and biological properties of a new peptide derived from MccJ25. We prepared a MccJ25-derived peptide containing 14 amino acids and a single intra-molecular disulfide bond a...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2019
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2019.33.1_supplement.670.10